Dipankar Bandyopadhyay

IIT Guwahati, India

Microfluidic Nanobiosensors Targeting Multiplexed Diagnostics on a Chip

The vision of improving the quality of human health not only requires state-of-art and frugal diagnostic facilities accessible to the ‘last mile’ population but also an ecosystem for the best practices and utilization. In this direction, the existing ecosystem and the conventional diagnostic facilities face limitations with institution based centralized operation, costly installation-operating-maintenance, expert dependency in analysis, and limited accessibility. Recently, a flurry of research activities has been observed in the design and development of user operated ultra-fast, affordable, and portable point-of-care-testing (POCT) devices to bridge this gap and provide information on the quality of health at the patient’s site before consulting the doctors. The modern-day machine learning and artificial intelligence tools integrated to the POCT devices have been able to guide the user to take care of critical parameters. For example, the glucometer, pregnancy kit, weighing machine, or pressure monitoring device connected to the mobile phones are some examples, which are very successful even at the commercial levels. Importantly, the software part has started playing an important role not only to setup a user-friendly ecosystem but also to enable best practices while using the hardware. At this stage, there is an urgent need to develop such POCT devices specific to many biomarkers such as enzymes, hormones, electrolytes, cytokines, interleukins, protein/fat/carb markers, and excretory molecules in the various body fluids such as serum, sebum, urine, saliva, or tear. A complete healthcare solution can be thought of development of such POCT technologies alongside the development of, (i) software for collection, storage and analysis, (ii) manpower for primary care, and (iii) a health management system, around the existing healthcare ecosystem. In bits and pieces, we are able to join many of these points, which will be the center point of this talk on the dream “Healthcare for a Billion”.

Dr. Dipankar Bandyopadhyay is a B.Sc in Chemistry and B.Tech in Chemical Engineering from Calcutta University. After completion of M.Tech from the Department of Chemical Engineering at IIT Kanpur, he served ANSYS – Fluent India Private Limited for more than 3 years as a CFD Engineer before completing PhD from IIT Kanpur. Presently, he is a Professor in the Department of Chemical Engineering and served as Head at the Centre for Nanotechnology & School of Health Sciences and Technology at IIT Guwahati. He has also served as visiting faculty at Yeungnam Univerisity at South Korea under the WCU Program, and KTH Sweden under the Erasmus Mundus program.

His research areas encompass Thin film Dynamics, Soft-matter Physics, Liquid Crystals and Smart Materials, Droplet and Digital Microfluidics, Health Care Point-of-Cater-Testing Devices, MEMS Theranostics, Microrheology, Clean energy, Harvesting, Computational Fluid Dynamics, Stability and Instability of Fluidic systems, Complex
Fluids, Microrheology, among others.

He has authored ~130 research publications in the international journals and has filed 21 Indian and 9 international patents so far. He is also one of the PIs of “Centre for Excellence on the Research and Development of Nanoelectronic Theranostic Devices”,
“Centre for Excellence in Disruptive Innovations & Product Development for Affordable Rural Healthcare”, and BioNEST at IIT Guwahati. He delivered Prof. C. V. Seshadri Memorial Distinguished Lecture 2020, IIT Kanpur. He is the recipient of NCL’s Prof. K
Venkataraman CHEMCON Award in CHEMCON 2016. He and his group at the Indian Institute of Technology Guwahati is the recipients of Gandhian Young Technology award 2016 and 2019, BIRAC-SRISTI Appreciation Award 2017 and 2021. He is a nominated member of American Chemical Society, Royal Society of Chemistry, and Indian Institute of Chemical Engineers.

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